Read all about QEWDjs- a leading edge NodeJS Integration framework
One good place to start is this introductory article on QEWD
In summary: QEWDjs is a Node.js-based platform for developing and running interactive browser-based applications and Web/REST services.
QEWD includes an embedded persistent JSON database and session store/cache using Global Storage provided by either the Redis, GT.M or Cache databases.
A single instance of QEWD can simultaneously support multiple browser-based applications and Web/REST services.
QEWD uses Express to provide its outward-facing HTTP(S) interface, and Socket.io to provide its outward-facing Web-socket interface.